BDBM575977 US11466016, Example 110::[6-(4-amino-4- methylpiperidin-1- yl)-3-(3,4-dichloro- 2-methyl-2H- indazol-5-yl)-1H- pyrazolo[3,4- b]pyrazin-5- yl]methanol

SMILES Cn1nc2ccc(-c3n[nH]c4nc(N5CCC(C)(N)CC5)c(CO)nc34)c(Cl)c2c1Cl

InChI Key InChIKey=UOQFDYWXYICJJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575977   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM575977(US11466016, Example 110 | [6-(4-amino-4- methylpip...)
Affinity DataIC50: 7nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2022
Entry Details
US Patent