BDBM5759 3-(4-Methoxyphenyl)-5-(4-picolylcarbamoyl)aminoindeno[1,2-c]pyrazol-4-one::3-[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]-1-(pyridin-4-ylmethyl)urea::Indenopyrazole 11e

SMILES COc1ccc(cc1)-c1n[nH]c2-c3cccc(NC(=O)NCc4ccncc4)c3C(=O)c12

InChI Key InChIKey=PDHGOPVHZSWSKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5759   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5759(3-(4-Methoxyphenyl)-5-(4-picolylcarbamoyl)aminoind...)
Affinity DataIC50: 29nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5759(3-(4-Methoxyphenyl)-5-(4-picolylcarbamoyl)aminoind...)
Affinity DataIC50: 1.15E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2005
Entry Details Article
PubMed