BDBM575785 US11466003, Compound 3::US11466003, Compound 56

SMILES CNC(=O)c1cnc2ccc(cn12)-c1ccccc1-c1cccc(C)n1

InChI Key InChIKey=NPXWPYHISGWKRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 575785   

TargetTGF-beta receptor type-1(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM575785(US11466003, Compound 3 | US11466003, Compound 56)
Affinity DataIC50: 19nMAssay Description:1. Preparation of kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Preparation of the compound: the final concentration of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM575785(US11466003, Compound 3 | US11466003, Compound 56)
Affinity DataIC50: 27nMAssay Description:1. Preparation of kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Preparation of the compound: the final concentration of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent