BDBM575720 US11465982, Example 1.20

SMILES CC(=O)N1CCN(c2ccc(CNC(=O)C3(CC3)c3ccc(OCc4ccc(nc4)C(F)(F)F)nn3)cc2)C(C)(C)C1

InChI Key InChIKey=WXPOGCNSAPTXLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575720   

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM575720(US11465982, Example 1.20)
Affinity DataIC50: 4nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2, 1 mM MgCl2 0.14 mM NaCl, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent