BDBM575653 (6-((2-amino-3-chloropyridin-4-yl)thio)-3- (4-amino-8-azadispiro- [2.1.55.23]dodecan-8-yl)pyrazin-2- yl)methanol::US11459340, Compound 35

SMILES NC1C2(CC2)CCC11CCN(CC1)c1ncc(Sc2ccnc(N)c2Cl)nc1CO

InChI Key InChIKey=FAAUYWWPEKEBLF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575653   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandPNGBDBM575653(US11459340, Compound 35 | (6-((2-amino-3-chloropyr...)
Affinity DataIC50: 3nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
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