BDBM575635 US11464802, Compound 4

SMILES Cn1cnnc1CC1(COC1)c1cccc(c1)N1Cc2c(cc(CN3CCCC(CC#N)C3)cc2C(F)(F)F)C1=O

InChI Key InChIKey=XBUWVXMAWVXPJO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 575635   

TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Human)
Nurix Therapeutics

US Patent

LigandBDBM575635(US11464802, Compound 4)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/11/2022
Entry Details
Copy Entry DOIGo to US Patent

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TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM575635(US11464802, Compound 4)Copy SMILESCopy InChI

Affinity DataIC50: 1nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL