BDBM575413 6-[[6-[3-(1,1-Difluoroethyl)phenyl]pyrazin-2-yl]methyl]-8-oxa- 6-azaspiro[2.5]octan-7-one::US11459336, Example 48

SMILES CC(F)(F)c1cccc(c1)-c1cncc(CN2CCC3(CC3)OC2=O)n1

InChI Key InChIKey=AHBCQOSOOAJGBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575413   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575413(US11459336, Example 48 | 6-[[6-[3-(1,1-Difluoroeth...)
Affinity DataIC50: 124nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent