BDBM575406 (5S)-3-[[6-[3-(1,1-Difluoroethyl)phenyl]pyrazin-2-yl]methyl]- 5-methyl-oxazolidin-2-one::US11459336, Example 41

SMILES C[C@H]1CN(Cc2cncc(n2)-c2cccc(c2)C(C)(F)F)C(=O)O1

InChI Key InChIKey=UJNMJERYEYGLSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575406   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575406(US11459336, Example 41 | (5S)-3-[[6-[3-(1,1-Difluo...)
Affinity DataIC50: 167nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent