BDBM575399 (4S)-3-[[6-[4-Chloro-3-(difluoromethoxy)phenyl]pyrazin-2- yl]methyl]-4-methyl-oxazolidin-2-one::US11459336, Example 34

SMILES C[C@H]1COC(=O)N1Cc1cncc(n1)-c1ccc(Cl)c(OC(F)F)c1

InChI Key InChIKey=NXELEXWMOSZDLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575399   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575399(US11459336, Example 34 | (4S)-3-[[6-[4-Chloro-3-(d...)
Affinity DataIC50: 86nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent