BDBM575372 (4R)-3-[[6-[3-(Difluoromethyl)-4-fluoro-phenyl]pyrazin-2- yl]methyl]-4-methyl-oxazolidin-2-one::US11459336, Example 7

SMILES C[C@@H]1COC(=O)N1Cc1cncc(n1)-c1ccc(F)c(c1)C(F)F

InChI Key InChIKey=VWBYIDAJHOHANQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575372   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575372(US11459336, Example 7 | (4R)-3-[[6-[3-(Difluoromet...)
Affinity DataIC50: 288nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent