BDBM575189 US11459329, Example 63::US11459329, Example 65

SMILES CN(C)Cc1ccc(cc1)-c1cc2ncc(-c3ccnc4nc(ccc34)-n3ncc(C)n3)n2nc1C

InChI Key InChIKey=UCIPHPBNGBTFNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 575189   

TargetActivin receptor type-1 [147-509](Human)
Incyte

US Patent
LigandPNGBDBM575189(US11459329, Example 63 | US11459329, Example 65)
Affinity DataIC50: 3nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetActivin receptor type-1 [147-509](Human)
Incyte

US Patent
LigandPNGBDBM575189(US11459329, Example 63 | US11459329, Example 65)
Affinity DataIC50: 3nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent