BDBM574760 2,3-Bis(4-phenylpiperidin-1-yl)quinoxaline-6-carboxylic Acid::US11459307, Example 30

SMILES OC(=O)c1ccc2nc(N3CCC(CC3)c3ccccc3)c(nc2c1)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=XKCVTJZYYCAGBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 574760   

LigandPNGBDBM574760(US11459307, Example 30 | 2,3-Bis(4-phenylpiperidin...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

LigandPNGBDBM574760(US11459307, Example 30 | 2,3-Bis(4-phenylpiperidin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent