BDBM574510 US11458149, Compound I-63

SMILES C[C@H](N1CCC(CC1)NC(=O)C=C)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=AGUJPRCSAORCQL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574510   

TargetTranscriptional enhancer factor TEF-1(Human)
Ikena Oncology

US Patent
LigandPNGBDBM574510(US11458149, Compound I-63)
Affinity DataEC50:  300nMAssay Description:TEAD inhibition can be assayed using Hippo Pathway TEAD Reporter MCF7 Cell Line (BPS Bioscience, Catalog #: 60618).More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent