BDBM574494 US11458149, Compound I-47

SMILES FC(F)(F)c1cccc(CN2CCC[C@H](C2)NC(=O)C=C)c1

InChI Key InChIKey=HFLGDQOTTKANCN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574494   

TargetTranscriptional enhancer factor TEF-1(Human)
Ikena Oncology

US Patent
LigandPNGBDBM574494(US11458149, Compound I-47)
Affinity DataEC50: >500nMAssay Description:TEAD inhibition can be assayed using Hippo Pathway TEAD Reporter MCF7 Cell Line (BPS Bioscience, Catalog #: 60618).More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent