BDBM573916 2-amino-9-[(2R,5S,7R,8R,10R, 12aR,14R,15R,15aS)-14-(6-amino-9H-purin-9- yl)-2,10,15-trihydroxy-2,10-disulfidooctahydro- 12H-5,8-methanofuro[3,2-1][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 86

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H]2C[C@@H]1O[P@@](S)(=O)OC[C@H]1O[C@H]([C@@H](O)C1O[P@@](S)(=O)OC2)n1cnc2c(N)ncnc12

InChI Key InChIKey=KSMLTSUHKLWPEA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 573916   

LigandPNGBDBM573916(US11453697, Example 86 | 2-amino-9-[(2R,5S,7R,8R,1...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573916(US11453697, Example 86 | 2-amino-9-[(2R,5S,7R,8R,1...)
Affinity DataEC50:  2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573916(US11453697, Example 86 | 2-amino-9-[(2R,5S,7R,8R,1...)
Affinity DataEC50:  2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent