BDBM573915 2-amino-9-[(5R,7R,8R,12aR,14R,15aS,16R)-14- (6-amino-9H-purin-9-yl)-2,10,16-trihydroxy- 2,10-disulfidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one (Diastereomer 2)::US11453697, Example 84::US11453697, Example 85

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)OC3C[C@@H](O[C@@H]3COP(S)(=O)O[C@H]1C2O)n1cnc2c(N)ncnc12

InChI Key InChIKey=NWYJEXFQCOWSKR-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 573915   

LigandPNGBDBM573915(US11453697, Example 85 | 2-amino-9-[(5R,7R,8R,12aR...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573915(US11453697, Example 85 | 2-amino-9-[(5R,7R,8R,12aR...)
Affinity DataEC50:  6.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573915(US11453697, Example 85 | 2-amino-9-[(5R,7R,8R,12aR...)
Affinity DataEC50:  6.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent