BDBM573902 1-[(5R,7R,8R,12aR,14R,15R,15aS,16R)- 14-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7- yl)-2,10,15,16-tetrahydroxy-2,10- dioxidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]- 1,5-dihydro-4H-imidazo[4,5-c]pyridin-4- one::US11453697, Example 61

SMILES Nc1ncnc2n(ccc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(=O)O[C@H]2[C@H]1O)O[C@H]3n1cnc2c1cc[nH]c2=O

InChI Key InChIKey=CRDJEMSLODILCE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 573902   

LigandPNGBDBM573902(US11453697, Example 61 | 1-[(5R,7R,8R,12aR,14R,15R...)
Affinity DataEC50:  18.2nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573902(US11453697, Example 61 | 1-[(5R,7R,8R,12aR,14R,15R...)
Affinity DataEC50:  379nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent