BDBM573886 2-amino-9- [(5S,7R,8R,12aR,14R,15R,15aS)-14-(4- amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)- 2,10,15-trihydroxy-2,10-dioxidooctahydro- 12H-5,8-methanofuro[3,2- l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]- 1,9-dihydro-6H-purin-6-one::US11453697, Example 45

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H]2C[C@H]1OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(=O)OC2)n1ccc2c(N)ncnc12

InChI Key InChIKey=XRGFJPKWFXRXMS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 573886   

LigandPNGBDBM573886(US11453697, Example 45 | 2-amino-9- [(5S,7R,8R,12a...)
Affinity DataEC50:  24.8nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573886(US11453697, Example 45 | 2-amino-9- [(5S,7R,8R,12a...)
Affinity DataEC50:  105nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent