BDBM573851 2-amino-9- [(5R,7R,8R,12aR,14R,15S,15aR,16R)-14-(6- amino-9H-purin-9-yl)-15-chloro-2,10,16- trihydroxy-2,10-dioxidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one::US11453697, Example 15

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@@H](COP(O)(=O)O[C@@H]1[C@@H]2O)O[C@H]([C@H]3Cl)n1cnc2c(N)ncnc12

InChI Key InChIKey=MHKGKEWFLINTRR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 573851   

LigandPNGBDBM573851(US11453697, Example 15 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50:  378nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent