BDBM573846 (5R,7R,8R,12aR,14R,15aS,16R)-7-(2-amino-6- oxo-1,6-dihydro-9H-purin-9-yl)-14-(4-amino- 7H-pyrrolo[2,3-d]pyrimidin-7-yl)-16- hydroxyoctahydro-12H-5,8-methanofuro[3,2-l] [1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecine- 2,10-diolate 2,10-dioxide::US11453697, Example 10

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)OC3C[C@@H](O[C@@H]3COP(O)(=O)O[C@H]1C2O)n1ccc2c(N)ncnc12

InChI Key InChIKey=IZYDPFDOPGWCRD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 573846   

LigandPNGBDBM573846(US11453697, Example 10 | (5R,7R,8R,12aR,14R,15aS,1...)
Affinity DataEC50:  4.90nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573846(US11453697, Example 10 | (5R,7R,8R,12aR,14R,15aS,1...)
Affinity DataEC50:  23.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent