BDBM573840 (5R,7R,8R,12aR,14R,15R,15aR,16R)-7,14-bis(6- amino-9H-purin-9-yl)-15-fluoro-16- hydroxyoctahydro-12H-5,8-methanofuro[3,2-l] [1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine- 2,10-diolate 2,10-dioxide::US11453697, Example 4

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]3C(O)[C@@H](COP(O)(=O)OC2[C@@H]1F)O[C@H]3n1cnc2c(N)ncnc12

InChI Key InChIKey=AKJJTMOTMKBURB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 573840   

LigandPNGBDBM573840(US11453697, Example 4 | (5R,7R,8R,12aR,14R,15R,15a...)
Affinity DataEC50:  22nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573840(US11453697, Example 4 | (5R,7R,8R,12aR,14R,15R,15a...)
Affinity DataEC50:  43.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent