BDBM573126 2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)-N-(4-(pyridin-2-yl)thiazol-2-yl)propanamide::US11453663, Preparative Example 169

SMILES CC(C)(C)c1cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccn2)cc(c1O)C(C)(C)C

InChI Key InChIKey=UZGCMQVKPLLHKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 573126   

TargetDouble-strand break repair protein MRE11(Human)
Masarykova Univerzita

US Patent
LigandPNGBDBM573126(US11453663, Preparative Example 169 | 2-cyano-3-(3...)
Affinity DataIC50: 5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent