BDBM572580 N-(4-{3-[1-(4-Methoxy-benzyl)-1H-pyrazol-4-ylmethyl]-ureido}-phenyl)-benzenesulfonamide::US11452717, Example 343

SMILES COc1ccc(Cn2cc(CNC(=O)Nc3ccc(NS(=O)(=O)c4ccccc4)cc3)cn2)cc1

InChI Key InChIKey=GDQLISLYOVIYKB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 572580   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572580(US11452717, Example 343 | N-(4-{3-[1-(4-Methoxy-be...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
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Date in BDB:
12/4/2022
Entry Details
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