BDBM571995 2-(((alphaR)-6-(3-(3-(2- hydroxy-2- methylpropoxy) phenyl)-2,5- dioxoimidazolidin- 1- yl)spiro[3.3]heptan- 2- yl)oxy)nicotinamide::US11447487, Example 88

SMILES CC(C)(O)COc1cccc(c1)N1CC(=O)N([C@H]2C[C@@]3(C[C@@H](C3)Oc3ncccc3C(N)=O)C2)C1=O

InChI Key InChIKey=CAWJJSORPGTRQN-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571995   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571995(2-(((alphaR)-6-(3-(3-(2- hydroxy-2- methylpropoxy)...)
Affinity DataIC50: 55nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent