BDBM571976 2-{[(alphaR)-6-[4- ({bicyclo[2.2.1]- heptan-2-yl]}- methyl)-2,5-dioxo- imidazolidin-1-yl]- spiro[3.3]heptan- 2-yljoxy}pyridine- 3-carboxamide::US11447487, Example 69

SMILES NC(=O)c1cccnc1O[C@H]1C[C@]2(C1)C[C@@H](C2)N1C(=O)NC(CC2CC3CCC2C3)C1=O

InChI Key InChIKey=AHXXDQYPMRQQHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571976   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571976(2-{[(alphaR)-6-[4- ({bicyclo[2.2.1]- heptan-2-yl]}...)
Affinity DataIC50: 16nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent