BDBM571946 2-{[(alphaR)-6-[4-(2- methylpentyl)-2,5- dioxoimidazolidin- 1-yl]spiro[3.3]- heptan-2-yl]oxy}- pyridine-3-carbox- amide::US11447487, Example 39

SMILES CCCC(C)CC1NC(=O)N([C@H]2C[C@@]3(C[C@@H](C3)Oc3ncccc3C(N)=O)C2)C1=O

InChI Key InChIKey=MZTQTMSGUPLGGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571946   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571946(2-{[(alphaR)-6-[4-(2- methylpentyl)-2,5- dioxoimid...)
Affinity DataIC50: 14nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent