BDBM571937 2-{[(alphaR)-6-[(4S)- 4-[2-(methyl- sulfanyl)ethyl]- 2,5-dioxoimidazol- idin-1-yl]spiro- [3.3]heptan-2-yl]- oxy}pyridine-3- carboxamide::US11447487, Example 30

SMILES CSCC[C@@H]1NC(=O)N([C@H]2C[C@@]3(C[C@@H](C3)Oc3ncccc3C(N)=O)C2)C1=O

InChI Key InChIKey=MDMQPCWFSQWDQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571937   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571937(2-{[(alphaR)-6-[(4S)- 4-[2-(methyl- sulfanyl)ethyl...)
Affinity DataIC50: 89nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent