BDBM571910 2-{[6-(2,5-dioxo- 3-phenylimidazol- idin-1-yl)spiro- [3.3]heptan-2-yl]- oxy}pyridine-3- carboxamide::US11447487, Example 3

SMILES NC(=O)c1cccnc1OC1CC2(C1)CC(C2)N1C(=O)CN(C1=O)c1ccccc1

InChI Key InChIKey=GIILBOOEKVDWPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571910   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571910(2-{[6-(2,5-dioxo- 3-phenylimidazol- idin-1-yl)spir...)
Affinity DataIC50: 9nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent