BDBM571731 BDBM50551166::Synthetic Route of N-(3-bromo-4-fluorophenyl)-N′-hydroxyl-4-(((1-sulfamoylpyrrolidin-3-yl)methyl)amino)-1,2,5-oxadiazole-3-formamidine ::US11447477, Compound 7

SMILES NS(=O)(=O)N1CCC(CNc2nonc2\C(Nc2ccc(F)c(Br)c2)=N\O)C1

InChI Key InChIKey=PTMVAXIURPPRBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 571731   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM571731(BDBM50551166 | Synthetic Route of N-(3-bromo-4-flu...)
Affinity DataIC50: 59nMAssay Description:The tested compounds and the reference compounds are dissolved in DMSO to prepare a high concentration of storage solution. The stock solution of ref...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM571731(BDBM50551166 | Synthetic Route of N-(3-bromo-4-flu...)
Affinity DataIC50: 123nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 30 mins by micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed