BDBM571436 3-{(3E)-3-[1-(3- methoxybenzoyl)-3,3- dimethylpiperidin-4- ylidene]prop-1-yn-1- yl}benzonitrile::US11440922, Example 196

SMILES COc1cccc(c1)C(=O)N1CC\C(=C/C#Cc2cccc(c2)C#N)C(C)(C)C1

InChI Key InChIKey=ZWDZNYOPBXSGBD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571436   

TargetMetabotropic glutamate receptor 5(Human)
Recordati Industria Chimica E Farmacentica

US Patent
LigandPNGBDBM571436(3-{(3E)-3-[1-(3- methoxybenzoyl)-3,3- dimethylpipe...)
Affinity DataEC50:  87.7nMAssay Description:The PAM potency was evaluated by performing an agonist concentration response curve in the presence of the compounds. The compounds at fixed concentr...More data for this Ligand-Target Pair
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Date in BDB:
11/19/2022
Entry Details
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