BDBM571435 US11440922, Example 137::{(4E)-4-[3-(3- chlorophenyl)prop-2-yn-1- ylidene]-3,3- dimethylpiperidin-1-yl}(3- methoxyphenyl)methanone

SMILES COc1cccc(c1)C(=O)N1CC\C(=C/C#Cc2cccc(Cl)c2)C(C)(C)C1

InChI Key InChIKey=GYUDNFZVPHGXKV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571435   

TargetMetabotropic glutamate receptor 5(Human)
Recordati Industria Chimica E Farmacentica

US Patent
LigandPNGBDBM571435({(4E)-4-[3-(3- chlorophenyl)prop-2-yn-1- ylidene]-...)
Affinity DataEC50:  268nMAssay Description:The PAM potency was evaluated by performing an agonist concentration response curve in the presence of the compounds. The compounds at fixed concentr...More data for this Ligand-Target Pair
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Date in BDB:
11/19/2022
Entry Details
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