BDBM571434 US11440922, Example 126::{(4E)-4-[3-(3- chlorophenyl)prop-2-yn-1- ylidene]-3,3- dimethylpiperidin-1-yl}(3- hydroxyphenyl)methanone

SMILES CC1(C)CN(CC\C1=C/C#Cc1cccc(Cl)c1)C(=O)c1cccc(O)c1

InChI Key InChIKey=QAGWFUCGRSXKGC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571434   

TargetMetabotropic glutamate receptor 5(Human)
Recordati Industria Chimica E Farmacentica

US Patent
LigandPNGBDBM571434({(4E)-4-[3-(3- chlorophenyl)prop-2-yn-1- ylidene]-...)
Affinity DataEC50:  115nMAssay Description:The PAM potency was evaluated by performing an agonist concentration response curve in the presence of the compounds. The compounds at fixed concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent