BDBM571399 US11440922, Example 19::ethyl (4E)-4-[3-(2,5- difluorophenyl)prop-2-yn- 1-ylidene]-3,3- dimethylpiperidine-1- carboxylate

SMILES CCOC(=O)N1CC\C(=C/C#Cc2cc(F)ccc2F)C(C)(C)C1

InChI Key InChIKey=UEYFUTHRQLEZHM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571399   

TargetMetabotropic glutamate receptor 5(Human)
Recordati Industria Chimica E Farmacentica

US Patent
LigandPNGBDBM571399(ethyl (4E)-4-[3-(2,5- difluorophenyl)prop-2-yn- 1-...)
Affinity DataKi:  0.890nMAssay Description:Affinity at transmembrane glutamate metabotropic cloned human mGluR5 receptor was evaluated according to the methods of Anderson (Anderson et al., J ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
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