BDBM571351 3-{2- acetamidoimidazo [1,2-b]pyridazin- 6-yl}-2-fluoro- N-{[2-fluoro-5- (trifluoromethoxy) phenyl] ($#194;2H$#226;,,)methyl}::US11440913, Example 430

SMILES CC(=O)Nc1cn2nc(ccc2n1)-c1c(C)ccc(C(=O)NCc2cc(OC(F)(F)F)ccc2F)c1F

InChI Key InChIKey=RSHCVMPDEIZBFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571351   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571351(US11440913, Example 430 | 3-{2- acetamidoimidazo [...)
Affinity DataIC50: 3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
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Date in BDB:
11/19/2022
Entry Details
US Patent