BDBM571340 5-{2- acetamidoimidazo [1,2-b]pyridazin-6- yl}-N-{[2-fluoro-5- (trifluoromethoxy) phenyl]methyl}-2-$#194;2H$#226;,f)methoxy- 4-methylbenzamid::US11440913, Example 417::US11440913, Example 421

SMILES COc1cc(C)c(cc1C(=O)NCc1cc(OC(F)(F)F)ccc1F)-c1ccc2nc(NC(C)=O)cn2n1

InChI Key InChIKey=WVBRDHUOKVQECG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 571340   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571340(US11440913, Example 421 | 5-{2- acetamidoimidazo [...)
Affinity DataIC50: 2nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571340(US11440913, Example 421 | 5-{2- acetamidoimidazo [...)
Affinity DataIC50: 4nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent