BDBM571321 (R)-5-(2- acetamidoimidazo [1,2-b]pyridazin- 6-yl)-N-(1- (2-fluoro-5- (trifluoromethoxy) phenyl)ethyl)-2- methylbenzamide::US11440913, Example 396

SMILES C[C@@H](NC(=O)c1cc(ccc1C)-c1ccc2nc(NC(C)=O)cn2n1)c1cc(OC(F)(F)F)ccc1F

InChI Key InChIKey=OBRPQVFAPLRLCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571321   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571321(US11440913, Example 396 | (R)-5-(2- acetamidoimida...)
Affinity DataIC50: 1nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent