BDBM571304 3-{2- acetamidoimidazo [1,2-b]pyridazin- 6-yl}-2,6- difluoro-N- [(1S)-1-[2- fluoro-5- (trifluoromethoxy)::US11440913, Example 379

SMILES C[C@H](NC(=O)c1c(F)ccc(c1F)-c1ccc2nc(NC(C)=O)cn2n1)c1cc(OC(F)(F)F)ccc1F

InChI Key InChIKey=MVKSEQIEJWREAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571304   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571304(US11440913, Example 379 | 3-{2- acetamidoimidazo [...)
Affinity DataIC50: 1nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
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Date in BDB:
11/19/2022
Entry Details
US Patent