BDBM571192 N-({2-[cyclopropyl(deutero)methoxy]- 3,5-difluorophenyl}methyl)-5-{2- acetamido-3-methylimidazo[1,2- b]pyridazin-6-yl}-2-methoxypyridine-3- carboxamide::US11440913, Example 259

SMILES COc1ncc(cc1C(=O)NCc1cc(F)cc(F)c1OCC1CC1)-c1ccc2nc(NC(C)=O)c(C)n2n1

InChI Key InChIKey=NKMGHZQIYYQPPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571192   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571192(N-({2-[cyclopropyl(deutero)methoxy]- 3,5-difluorop...)
Affinity DataIC50: 3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent