BDBM571088 N-{[2- (cyclobutylmethoxy)phenyl]methyl}-5- {2-acetamidoimidazo[1,2-b]pyridazin- 6-yl}-2-methoxypyridine-3- carboxamide::US11440913, Example 155

SMILES COc1ncc(cc1C(=O)NCc1ccccc1OCC1CCC1)-c1ccc2nc(NC(C)=O)cn2n1

InChI Key InChIKey=MSTGCINGCSESNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571088   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571088(N-{[2- (cyclobutylmethoxy)phenyl]methyl}-5- {2-ace...)
Affinity DataIC50: 2nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent