BDBM570984 N-({2- [cyclopropyl(deutero)methoxy]- 3,5-difluorophenyl}methyl)-5-{2- acetamidoimidazo[1,2-b]pyridazin- 6-yl}-2-(D3)methoxypyridine- 3-carboxamide::US11440913, Example 121::US11440913, Example 49::US11440913, Example 55

SMILES COc1ncc(cc1C(=O)NCc1cc(F)cc(F)c1OCC1CC1)-c1ccc2nc(NC(C)=O)cn2n1

InChI Key InChIKey=CXQXAXGVRWRAJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 570984   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM570984(US11440913, Example 55 | N-({2- [cyclopropyl(deute...)
Affinity DataIC50: 1nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM570984(US11440913, Example 55 | N-({2- [cyclopropyl(deute...)
Affinity DataIC50: 3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM570984(US11440913, Example 55 | N-({2- [cyclopropyl(deute...)
Affinity DataIC50: 3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent