BDBM569435 4-(1-(2-Chloro-3- ((methylamino)methyl) phenyl)-1H-imidazol- 4-yl)-N-(1- (methylsulfonyl) piperidin-4-yl)-5- (trifluoromethyl) pyrimidin-2-amine::US11427567, Example 462::US11427567, Example 80

SMILES CNCc1cccc(c1Cl)-n1cnc(c1)-c1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C(F)(F)F

InChI Key InChIKey=BZOULFDQZRPBSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 569435   

LigandPNGBDBM569435(US11427567, Example 462 | 4-(1-(2-Chloro-3- ((meth...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

LigandPNGBDBM569435(US11427567, Example 462 | 4-(1-(2-Chloro-3- ((meth...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent