BDBM569226 US11427561, Compound 35f::US11427561, Compound 35i

SMILES CC1(O)CC(C1)[C@H](N)c1cccc(n1)-c1ccc2cnn(-c3cccc(CF)n3)c2c1

InChI Key InChIKey=LTTZUCQYAOLWOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 569226   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM569226(US11427561, Compound 35i | US11427561, Compound 35...)
Affinity DataIC50: 100nMAssay Description:Biochemical Assay: The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM569226(US11427561, Compound 35i | US11427561, Compound 35...)
Affinity DataIC50: 550nMAssay Description:Biochemical Assay: The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent