BDBM569207 US11427561, Compound 20

SMILES N[C@@H]([C@@H]1C[C@H](O)C1)c1cccc(n1)-c1ccc2cnn(-c3cccc(n3)C3(CC3)C#N)c2c1

InChI Key InChIKey=ZAFIMMPUQBNUGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 569207   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM569207(US11427561, Compound 20)
Affinity DataIC50: 100nMAssay Description:Biochemical Assay: The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent