BDBM569200 (1R,3s)-3-((S)-amino(6-(1-(6-ethylpyridin-2-yl)-1H-indazol-6-yl)pyridin-2-yl)methyl)cyclobutanol::US11427561, Compound 12::US11427561, Compound 35b

SMILES CCc1cccc(n1)-n1ncc2ccc(cc12)-c1cccc(n1)[C@@H](N)C1CC(O)C1

InChI Key InChIKey=VTPSLBQSWFAYMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 569200   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM569200(US11427561, Compound 35b | (1R,3s)-3-((S)-amino(6-...)
Affinity DataIC50: 100nMAssay Description:Biochemical Assay: The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM569200(US11427561, Compound 35b | (1R,3s)-3-((S)-amino(6-...)
Affinity DataIC50: 100nMAssay Description:Biochemical Assay: The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent