BDBM568531 (R)-(3-aminopiperidin-1-yl)(2-(5,6-difluoro-1-(3-methoxybenzyl)-1H-indol-2-yl)-3-methylimidazo[1,2-a]pyridin-7-yl)methanone::US11426412, Compound 55

SMILES COc1cccc(Cn2c(cc3cc(F)c(F)cc23)-c2nc3cc(ccn3c2C)C(=O)N2CCC[C@@H](N)C2)c1

InChI Key InChIKey=RJCBATGNKMOYOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 568531   

TargetProtein-arginine deiminase type-4(Human)
Jubilant Epipad

US Patent
LigandPNGBDBM568531((R)-(3-aminopiperidin-1-yl)(2-(5,6-difluoro-1-(3-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:Citrullination assay was detected via ammonia release. PAD4 was diluted to 120 nM in assay buffer (100 mM HEPES, 50 mM NaCl, 2 mM DDT, 0.6 mg/mL BSA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent