BDBM568380 US11420975, Compound B-6-4

SMILES CC1(COC1)C(=O)NC12CCC(CC1)(C2)n1cc(-c2ccc(cc2)C(=O)Nc2cc(ccn2)C(F)(F)F)c2c(N)ncnc12

InChI Key InChIKey=VRRUYJCAQTYQAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568380   

TargetTyrosine-protein kinase BTK(Human)
TRANSTHERA SCIENCES (NANJING), INC.

US Patent
LigandPNGBDBM568380(US11420975, Compound B-6-4)
Affinity DataIC50: 5.5nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
TRANSTHERA SCIENCES (NANJING), INC.

US Patent
LigandPNGBDBM568380(US11420975, Compound B-6-4)
Affinity DataIC50: 5.5nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent