BDBM568374 US11420975, Compound A-16-2

SMILES COCCC(=O)NC12CCC(CC1)(C2)c1nc(-c2ccc(CNC(=O)c3cc(F)ccc3OC)cc2)c2c(N)nccn12

InChI Key InChIKey=CVKIKFONFFRUST-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568374   

TargetTyrosine-protein kinase BTK(Human)
TRANSTHERA SCIENCES (NANJING), INC.

US Patent
LigandPNGBDBM568374(US11420975, Compound A-16-2)
Affinity DataIC50: 5.5nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
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TargetTyrosine-protein kinase BTK [C481S](Human)
TRANSTHERA SCIENCES (NANJING), INC.

US Patent
LigandPNGBDBM568374(US11420975, Compound A-16-2)
Affinity DataIC50: 5.5nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent