BDBM568372 US11420975, Compound A-13-4::US12291534, Compound A-13-4

SMILES Nc1nccn2c(nc(-c3ccc(Oc4ccccc4)cc3)c12)C12CCC(CC1)(C2)NC(=O)CN1CCOCC1

InChI Key InChIKey=DGPCJHZDAQLPPM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 568372   

TargetTyrosine-protein kinase BTK(Human)
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568372(US11420975, Compound A-13-4 | US12291534, Compound...)
Affinity DataIC50: 30nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568372(US11420975, Compound A-13-4 | US12291534, Compound...)
Affinity DataIC50: 5.5nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568372(US11420975, Compound A-13-4 | US12291534, Compound...)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568372(US11420975, Compound A-13-4 | US12291534, Compound...)
Affinity DataIC50: 5.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent