BDBM567740 US11420968, Example F102

SMILES CO[C@@]1(C)CC[C@H](CNc2ccc(cc2[N+]([O-])=O)S(=O)(=O)NC(=O)c2ccc(cc2Oc2cnc3[nH]ccc3c2)N2CCC3(CC(C3)N3CCC[C@H]3c3ccccc3C(C)C)CC2)CC1

InChI Key InChIKey=PJXASAHBKOYFLH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 567740   

TargetApoptosis regulator Bcl-2(Human)
Beigene

US Patent
LigandPNGBDBM567740(US11420968, Example F102)
Affinity DataIC50: 0.0870nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2/Bcl-X protein with its ligand in an assay based on Time-Resolved Fluorescence Resonance ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Beigene

US Patent
LigandPNGBDBM567740(US11420968, Example F102)
Affinity DataIC50: 271nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2/Bcl-X protein with its ligand in an assay based on Time-Resolved Fluorescence Resonance ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Beigene

US Patent
LigandPNGBDBM567740(US11420968, Example F102)
Affinity DataIC50: 0.0870nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Beigene

US Patent
LigandPNGBDBM567740(US11420968, Example F102)
Affinity DataIC50: 271nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Beigene

US Patent
LigandPNGBDBM567740(US11420968, Example F102)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed