BDBM567417 US11420968, Example E12

SMILES [O-][N+](=O)c1cc(ccc1NCC1CCOCC1)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCC(CC1)N1CCCC1c1ccccc1C1CC1

InChI Key InChIKey=JPKVSVJCEXNAHM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 567417   

TargetApoptosis regulator Bcl-2(Human)
Beigene

US Patent
LigandPNGBDBM567417(US11420968, Example E12)
Affinity DataIC50: 7.20nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2/Bcl-xl protein with its ligand in an assay based on fluorescence polarization methodolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Beigene

US Patent
LigandPNGBDBM567417(US11420968, Example E12)
Affinity DataIC50: 763nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2/Bcl-xl protein with its ligand in an assay based on fluorescence polarization methodolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Beigene

US Patent
LigandPNGBDBM567417(US11420968, Example E12)
Affinity DataIC50: 0.990nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Beigene

US Patent
LigandPNGBDBM567417(US11420968, Example E12)
Affinity DataIC50: 763nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed